• 
  Huracan – Racing

  14 September

• 
  Independiente – San

  13 September

• 
  Argentinos Juniors – Gimnasia

  13 September

• 
  Sarmiento – Belgrano

  13 September

• 
  Tigre – Rosario Central

  13 September

• 
  Talleres de Cordoba – Union

  13 September

• 
  Atletico Tucuman – River

  12 September

• 
  Estudiantes LP – Atletico

  12 September

• 
  Independiente – Aldosivi

  12 September

• 
  Flamengo-RJ – Corinthians

  13 September

• 
  Mirassol – Vitoria-BA

  13 September

• 
  Santos-SP – Cruzeiro-MG

  13 September

• 
  Botafogo-RJ – RB

  13 September

• 
  Palmeiras – Sao Paolo

  12 September

• 
  Chapecoense – Inter-RS

  12 September

• 
  Gremio-RS – Vasco

  12 September

• 
  Atletico-MG – Fluminense

  12 September

• 
  Audax – O`Higgins

  14 September

• 
  Colo Colo – Deportes

  13 September

• 
  La Serena – Universidad

  13 September

• 
  Palestino – Universidad

  13 September

• 
  Cobresal – Coquimbo

  12 September

• 
  Cucuta – Millonarios

  14 September

• 
  Once Caldas – Deportivo

  14 September

• 
  Atletico Nacional – Aguilas

  13 September

• 
  Deportivo Pereira – Atl

  13 September

• 
  Alianza Valledupar – Atletico

  13 September

• 
  Boyaca Chico – Ind

  13 September

• 
  Inter – Llaneros

  12 September

• 
  Manchester Utd – Manchester

  13 September

• 
  Coventry City – Brighton

  13 September

• 
  Sunderland – Arsenal

  12 September

• 
  Tottenham – Everton

  12 September

• 
  Brest – PSG

  13 September

• 
  Le Mans – Lens

  13 September

• 
  Lille – Troyes

  13 September

• 
  Auxerre – Nice

  12 September

• 
  Lorient – Toulouse

  12 September

• 
  Le Havre – Angers

  12 September

• 
  Paris – Lyon

  12 September

• 
  Elversberg – Bayern

  13 September

• 
  RB Leipzig – Hamburg

  13 September

• 
  Cologne – Werder Bremen

  12 September

• 
  Sassuolo – Juventus

  13 September

• 
  Napoli – Bologna

  13 September

• 
  Lecce – Monza

  13 September

• 
  Atalanta – Cagliari

  12 September

• 
  Lazio – Milan

  12 September

• 
  Urawa Reds – Fagiano

  13 September

• 
  Tokyo Verdy – JEF

  13 September