• 
  Gimnasia Mendoza – Newell`s

  12 October

• 
  Lanus – Velez Sarsfield

  12 October

• 
  Talleres – Independiente

  12 October

• 
  Racing – Belgrano

  11 October

• 
  Bahia – Mirassol

  11 October

• 
  Arsenal – Lille

  13 October

• 
  Villarreal – Napoli

  13 October

• 
  RB Leipzig – PSV

  13 October

• 
  Sabah – Slavia Prague

  13 October

• 
  Lens – Sporting

  13 October

• 
  Universidad – Nublense

  12 October

• 
  Deportes – Palestino

  12 October

• 
  Coventry City – Newcastle

  12 October

• 
  Torino – Udinese

  12 October

• 
  Atalanta – Venezia

  12 October

• 
  Severstal – SKA

  13 October

• 
  Torpedo NN – Metallurg

  12 October

• 
  Shanghai Dragons – Dinamo

  12 October

• 
  Ak Bars – Sochi

  12 October

• 
  Barys – Sibir

  12 October

• 
  Salavat – Neftekhimik

  12 October

• 
  Amur – Lada Tl

  12 October

• 
  Pumas – Cruz Azul

  12 October

• 
  Pachuca – Necaxa

  12 October

• 
  Atletico de San Luis – Santos

  12 October

• 
  Famalicao – Alverca

  12 October

• 
  U Cluj – Rapid Bucuresti

  12 October

• 
  Arges Pitesti – CFR Cluj

  12 October

• 
  Levante – Sevilla

  12 October

• 
  Livyi Bereh – Zoria

  12 October

• 
  St Louis City – LA

  12 October

• 
  Cibona – Slovan

  12 October

• 
  Alex De Minaur – Karen

  13 October

• 
  Tommy Paul – Valentin

  12 October

• 
  Arthur Fils – Botic

  12 October

• 
  Zizou Bergs – Carlos

  12 October

• 
  Learner Tien – Casper

  12 October

• 
  HFX Wanderers – Cavalry

  12 October

• 
  Forge – Inter Toronto

  12 October

• 
  Pacific – Atletico

  12 October

• 
  Frolunda – Bordeaux

  13 October

• 
  Skelleftea – Salzburg

  13 October

• 
  Nitra – Rogle

  13 October

• 
  Dynamo – Vaxjoe

  13 October

• 
  Tychy – Tappara

  13 October

• 
  KooKoo – Adler Mannheim

  13 October

• 
  Trento – Chemnitz

  13 October

• 
  Lietkabelis – PAOK

  13 October

• 
  Neptunas – JL Bourg

  13 October

• 
  Bahcesehir – Manresa

  13 October