• 
  Talleres de Cordoba – Union

  13 September

• 
  Atletico Tucuman – River

  12 September

• 
  Estudiantes LP – Atletico

  12 September

• 
  Independiente – Aldosivi

  12 September

• 
  Boca Juniors – Central

  12 September

• 
  Defensa y Justicia – Gimnasia

  11 September

• 
  Newell`s Old Boys – Velez

  11 September

• 
  Santos-SP – Cruzeiro-MG

  13 September

• 
  Botafogo-RJ – RB

  13 September

• 
  Palmeiras – Sao Paolo

  12 September

• 
  Chapecoense – Inter-RS

  12 September

• 
  Gremio-RS – Vasco

  12 September

• 
  Atletico-MG – Fluminense

  12 September

• 
  Coritiba – Athletico-PR

  12 September

• 
  Palestino – Universidad

  13 September

• 
  Cobresal – Coquimbo

  12 September

• 
  Nublense – Everton VM

  12 September

• 
  Alianza Valledupar – Atletico

  13 September

• 
  Boyaca Chico – Ind

  13 September

• 
  Inter – Llaneros

  12 September

• 
  Santa Fe – Deportes

  12 September

• 
  Jaguares de Cordoba – Fortaleza

  12 September

• 
  Coventry City – Brighton

  13 September

• 
  Sunderland – Arsenal

  12 September

• 
  Tottenham – Everton

  12 September

• 
  Liverpool – Fulham

  12 September

• 
  Chelsea – Hull City

  12 September

• 
  Aston Villa – Nottingham

  12 September

• 
  Crystal Palace – Ipswich

  12 September

• 
  Bournemouth – Brentford

  12 September

• 
  Strasbourg – AS Monaco

  12 September

• 
  Rennes – Marseille

  11 September

• 
  RB Leipzig – Hamburg

  13 September

• 
  Cologne – Werder Bremen

  12 September

• 
  Mainz 05 – Eintracht

  12 September

• 
  Freiburg – Borussia M

  12 September

• 
  Augsburg – Leverkusen

  12 September

• 
  Hoffenheim – Stuttgart

  12 September

• 
  Dortmund – Paderborn

  12 September

• 
  Union Berlin – Schalke

  11 September

• 
  Lecce – Monza

  13 September

• 
  Atalanta – Cagliari

  12 September

• 
  Lazio – Milan

  12 September

• 
  Genoa – Frosinone

  12 September

• 
  Venezia – Fiorentina

  11 September

• 
  Machida Zelvia – Yokohama

  12 September

• 
  Sanfrecce Hiroshima – Cerezo

  12 September

• 
  V-Varen Nagasaki – Nagoya

  12 September

• 
  Gamba Osaka – Tokyo

  12 September

• 
  Shimizu S-Pulse – Avispa

  12 September