• 
  Instituto – Rio Cuarto

  15 September

• 
  Banfield – Barracas

  14 September

• 
  Deportivo – Lanus

  14 September

• 
  Huracan – Racing

  14 September

• 
  Independiente – San

  13 September

• 
  Union La Calera – Deportes

  15 September

• 
  Audax – O`Higgins

  14 September

• 
  America de Cali – Deportivo

  15 September

• 
  Cucuta – Millonarios

  14 September

• 
  Once Caldas – Deportivo

  14 September

• 
  Atletico Nacional – Aguilas

  13 September

• 
  Leeds Utd – Newcastle

  14 September

• 
  Inter – Udinese

  14 September

• 
  Torino – Roma

  14 September

• 
  Como – Parma

  14 September

• 
  Traktor – Lokomotiv

  15 September

• 
  Avangard – Avtomobilist

  15 September

• 
  Torpedo NN – Ak Bars

  14 September

• 
  Severstal – Dynamo Msk

  14 September

• 
  Lada Tl – Dinamo Mn

  14 September

• 
  Leon – Atletico

  15 September

• 
  Guadalajara – Pumas

  14 September

• 
  Santos Laguna – Juarez

  14 September

• 
  Braga – Estoril Praia

  14 September

• 
  Rio Ave – Estrela

  14 September

• 
  FCSB – Petrolul

  14 September

• 
  U Cluj – Otelul Galati

  14 September

• 
  Alaves – Valencia

  15 September

• 
  Rayo – Espanyol

  15 September

• 
  Villarreal – Real Betis

  14 September

• 
  Gaziantep – Fenerbahce

  14 September

• 
  Shakhtar – Chornomorets

  14 September

• 
  Dynamo Kyiv – Epitsentr

  14 September

• 
  San Diego – Philadelphia

  14 September

• 
  Vancouver – Austin

  13 September

• 
  Chicago Fire – New

  13 September

• 
  Al – Pakhtakor

  14 September

• 
  Al Quadisiya – Al Wasl

  14 September

• 
  Esteghlal – Al-Sadd

  14 September

• 
  Shabab Al Ahli – Tractor

  14 September

• 
  Al-Shamal – Al-Ittihad

  14 September

• 
  Shafa – Sabah

  14 September

• 
  Ludogorets – Septemvri

  14 September

• 
  Hebar – Etar

  14 September

• 
  Pacific – Cavalry

  13 September

• 
  Orsomarso – Atletico

  14 September

• 
  Tigres Bogota – Bogota

  14 September

• 
  Deportes Quindio – Patriotas

  14 September

• 
  Gorica – Varazdin

  14 September

• 
  Romania – Turkey

  14 September